Department of Pediatric and Adolescent Medicine of the First Faculty of Medicine and General University Hospital provides outpatient, institutional diagnostic and therapeutic care in the field of pediatric medicine and its specializations, neonatology and adolescent medicine, including transport services for critically ill children. In patients with long-term follow-up who cannot be transferred to internal care (hereditary metabolic disorders and some other narrow specializations), they also take care of patients over 19 years of age. It provides highly specialized neonatological care for the Central Bohemian Region, nationwide care in the field of hereditary metabolic disorders and provides all-population neonatal screening for hereditary metabolic disorders.
Almost half of the patients are out of Prague and are admitted to the clinic at the request of general practitioners for children and adolescents, outpatient specialists or inpatient wards. The mandatory catchment area of the KDDL is Prague 1, 2 and 4. Most younger children are admitted to hospital with an escort.
Highlighted fields of KDDL are pediatric and neonatal intensive care and resuscitation unit (JIRP), including the possibility of providing unconventional methods of artificial pulmonary ventilation and haemoelimination methods, diagnostics and therapy in the field of hereditary metabolic disorders. diseases. Equally important is the care of children with connective tissue and skeletal disorders, gastrointestinal disorders including nutritional disorders, diagnostics and therapy of congenital uropathy (in cooperation with the Department of Urology, First Faculty of Medicine, Charles University and General Teaching Hospital). In April 2011, a new outpatient facility was opened within the KDDL - the Comprehensive Care Center for Children with Perinatal Load.
As of 1 September 2017, the Department of Inherited Metabolic Disorders was merged with the Department of Pediatric and Adolescent Medicine. All services provided in the area of diagnostics and health care remain unchanged, as well as research and teaching activities.
DMP diagnostic laboratories carry out specialized laboratory examinations for diagnosis and monitoring of patients in the field of biochemical genetics and related fields, screening of hereditary metabolic disorders in newborns born in cooperating maternity hospitals and provide continuous emergency service for selected statim examinations, including medical consulting. The basis of the activity is laboratory diagnostics of several hundred DMPs at different levels (metabolite, enzyme / protein, tissue / cell, gene) in the laboratory of biochemical / metabolic, enzymological, histochemical and molecular genetic. About 3,000 new patients with suspected DMP are examined each year and a diagnosis is made in approximately 100 patients a year.